Sarah Eustis-Guthrie: Why Malaria Giving Makes Sense #22

Can rigorous research be an act of love? JD explores this theme with Sarah Eustis-Guthrie, a program officer GiveWell, the world's leading charity evaluator, where she helps direct over $150 million a year towards the most cost-effective malaria interventions. A University of Chicago graduate who came to Christian faith through a church choir, Sarah previously co-founded Maternal Health Initiative, a family planning non-profit working in Ghana.

Note: This episode was filmed in early 2025; the USAID/PEPFAR situation has evolved since then. Also, Sarah is now a Program Officer for Malaria. She speaks here in her personal capacity, not on behalf of GiveWell or its affiliates.

Articles, Scripture, organisations, and other media discussed in this episode

Mentioned Scripture


Episode Highlights:

We Know How to Stop Malaria—But Don’t

“But the thing about malaria is that we know how to stop kids from dying from malaria. We know how to diagnose malaria. We know how to prevent malaria. And we know how to treat malaria. It's not a mystery. The reason why all these kids are dying of malaria is because the global community has decided not to invest the resources in saving those lives.

Moral Thinking & Technology

“You know, back in the time of Jesus, it wouldn't have been possible for someone to click a button on a website and donate money that would have gone to help save someone's life who was thousands of miles away. And so I think, you know, I think actually one of the reasons our society struggles with this so much, I think one of the reasons that our world is so inequitable is I don't think our like moral thinking has totally caught up to these technological changes.”

Dealing with Discouragement

“And I remember one thing someone told me when I was feeling really bummed about the org not working out. And they said, you're just on the unlucky side of an expected value bet. So you make a bet that says, this might not work out, but if it does, it's great. And what happens when you bet is that you lose some of the time, right? And I think we have to find ways of being OK with that.

“So I remember one thought I had that was really reassuring when I was struggling with the charity not working out was thinking about the fact that many people had actually started thinking about founding our charity and then had instead decided to start other really impactful charities, charities that have saved a lot of lives, a lot of human lives, a of animal lives that have reduced suffering. ”

Can Everyday Choices Save Lives?

“And I think that it's, it's just true that there's really easy trade-offs that folks who are well off can make, where you save a lot of money that could genuinely save people's lives.  And I think there's something a bit grotesque about our culture that we don't reckon with this more. I don't think about it all the time, because that would drive me crazy.  I think for me, it's something I think about.”

Resume from here

Love Drives the Numbers

“Yeah, I think people often get really hung up on this alleged ruthlessness, right? I think people often have the sense of as soon as you're breaking out the numbers that that means that you're not thinking about other things, whether it be equity or whether it be love and care. I guess I'd say that my own quantification focus like really springs out of love and care. And I think for me, as I'm practicing it, I feel that it continues to be deeply shaped by that love and care.

You know, I think at the end of the day, the reason I do this work is because there's kids out there, you know, who are dying of terrible diseases, where they're, you know, in pain, they're suffering, they die and their loved ones have to grieve them. And that's just this horrible tragedy.”

Global Development Needs More Talent

“I think honestly, one of my biggest surprises from the last couple of years of working in development  is how talent constrained so many organizations are. So I can think of five different organizations off the top of my head where they did a hiring round, they couldn't find the right person for that job. And that ultimately meant that one person had to keep doing multiple responsibilities or they couldn't expand a certain program.  I think...

From the applicant perspective, it doesn't always feel like this  because I certainly had this experience of applying to tons of jobs and getting rejected from them.

Be Willing to Change Your Mind

“One of the most important ones is being open-minded and willing to update on new evidence.  I think a lot of people, especially who've been in development for a while,  have a very set idea of what works and what doesn't, and they're not willing to update based on new evidence. So being willing to come in with a take and then change that take appropriately based on evidence is really important.”



 

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